Nodulocystic Acne: Identification, Treatment, & Prevention
Nodulocystic acne forms as a result of an unfortunate combination of clogged pores, trapped bacteria, and genetic predisposition. This kind of acne presents itself as painful, hard, and liquid-filled bumps deep beneath the skin that don't respond to traditional over-the-counter treatments. Many patients find this type of acne painful and uncomfortable.
If you are struggling with stubborn, persistent, and painful acne, reach out to your local dermatologist today. Professional acne treatment can help minimize scarring, reduce future breakouts, and improve both your skin and your quality of life. Reach out to Gainesville Dermatology Skin Surgery to schedule your consultation today!
What Is Nodulocystic Acne?
Nodulocystic acne is a type of nodular acne that also involves the presence of pus-filled cysts beneath the skin. Like nodular acne, this kind of breakout forms when clogged pores contain trapped bacteria (Cutibacterium acnes) that reproduce deep within the skin, resulting in significant inflammation. In nodulocystic breakouts, this inflammation causes hair follicles to rupture, sending your body's immune system into overdrive. As a result, characteristic pus-filled cysts form, resulting in intense inflammation, pain, and overall discomfort.
On the surface, this kind of acne presents itself as hard, sometimes red, lumps beneath the skin. The lumps may feel firm, tender, or swollen, depending on the amount of inflammation and fluid beneath the skin. There usually is not a visible "whitehead" on the skin's surface.
What Causes Nodulocystic Acne?
Nodulocystic acne typically forms under a very unique set of circumstances. Excess oil production, hormonal changes, genetics, inflammation, and overgrowth of acne-associated bacteria can all contribute to nodulocystic acne. In particular, nodulocystic acne tends to affect adolescent males, those experiencing extreme hormone fluctuations, and those with hyperhidrosis more often.
Nodulocystic Acne Treatment
Treatment for nodulocystic acne is very similar to that of regular nodular acne. Over-the-counter treatments, such as topical acne ointment or skin care regimens, cannot penetrate the skin enough to effectively treat this kind of acne. Do not pick at or attempt to drain this kind of acne on your own, as nodulocystic acne scars are deep, common, and difficult to hide.
Severe nodular acne treatments prescribed by our Gainesville dermatologists frequently include a combination of the following topical, oral, and injected medications:
- Oral Birth Control
- Isotretinoin
- Tetracycline (a type of antibiotic)
- Prescription Creams (containing benzoyl peroxide, salicylic acid, and strong retinoids)
- Diluted Corticosteroid Injections
How To Prevent Nodular Acne
The best way to limit the formation of nodular acne is by maintaining a strict skincare routine. Wash your face frequently, and use only non-comedogenic, acne-friendly products. In general, nodular acne is difficult to eliminate without professional treatment of some kind.
If you are struggling with stubborn, persistent, or painful acne, reach out to a local dermatologist for help. Professional acne treatment can help reduce inflammation, minimize the risk of scarring, limit future breakouts, and improve both your skin and your quality of life. Contact Gainesville Dermatology Skin Surgery to schedule your consultation today.

